Recombinant SIRT6 protein

Aliases: SIR2L6
Catalog No: 31336 Format: 25 µg Discontinued

Expressed In: E. coli Protein Species: Human

Contents

A representative Technical Data Sheet (TDS) is provided here. Please refer to the lot-specific TDS you will receive with your order for the lot-specific buffer contents and protein concentration.

Application Notes

Recombinant SIRT6 is suitable for use in histone deacetylase assays. A recommended starting point for the HDAC assay is 20-100 ng of recombinant protein per reaction.

Protein Details

SIRT6 is a histone and protein deacetylase, an NAD-dependant enzyme that removes acetyl groups from lysine acetylated proteins. SIRT6 has been shown to deacetylate histone H3 at lysine 9. Recombinant human SIRT6 was expressed in E. coli as the full length protein (accession number NM_016539) with an N-terminal GST-Tag. The molecular weight of the protein is ~65 kDa.

 

SIRT6 protein gel.
SIRT6 run on a 10% SDS-PAGE gel and stained with Coomassie blue. Arrow indicates recombinant SIRT6.

Guarantee

This product is guaranteed for 6 months from date of receipt.

This product is for research use only and is not for use in diagnostic procedures.